I want to thank all for creating the foundation and website. 9 years ago when I was diagnosed there was little information available. I had to do a lot of research on my own. The work you are doing is awesome! No one should ever die from anal cancer.

Maria

Since the Foundation’s inception in 2010 we have dedicated ourselves to improving the lives of anal cancer thrivers, supporting and funding research for anal cancer as well as HPV-related cancers, creating a collaborative space for clinicians to share knowledge and ideas, and moving the pendulum forward in increasing vaccination rates for girls and boys. We continue to work with leaders in the field to not only eradicate HPV-related cancers for future generations, but to eliminate research and scientific silos and bring improved and novel treatments to those diagnosed with anal cancer.

Our staff and boards work every day to improve the once bleak landscape facing the anal cancer community. It is our promise and commitment that tomorrow will  be different for our community!

The difference your 2016 contribution made

Investing in the Future

Investing in the Future

Immunotherapies

While immunotherapy research is in its infancy, we believe it holds promise for viral-initiated cancers like anal cancer, and are fighting to ensure you have access to these potential new drugs. That's why we are taking action to spur creation of the first new treatments for anal cancer in 42 years. The first Phase II study of the antibody Nivolumab in metastatic anal squamous cell carcinoma patients was completed at MD Anderson Cancer Center this year. The study is a first step in achieving a potential new drug for treatment-resistant anal cancer. The next phase will add a CTLA4 inhibitor to further analyze the most effective methods of therapy. Our multi-year initiative for novel HPV-related immunotherapy research at Dana-Farber Cancer Institute completed its molecular research phase, and will be launching a clinical trial in 2017. This research seeks new treatments for advanced staged HPV-related anal, cervical and oropharyngeal cancers.

Fighting for Equitable Cancer Prevention

Fighting for Equitable Cancer Prevention

HPVACTION: Give boys the vaccine!

Our UK advocacy, spearheaded by HPV Action (HPVA), saw phenomenal momentum this year. In the UK, boys remain without access to the cancer protection provided by the HPV vaccine. UK legislators showed their growing support for gender-neutral HPV vaccination by holding a parliamentary debate in June to discuss the issue. As a result of our collaborative work, HPV vaccination for boys was included as part of the All Party Parliamentary Group on Cancer Inquiry. HPVA also organized a letter from 13 medical experts to the UK Secretary of State for Health urging him to expedite a decision to extend the national HPV vaccination program to include all adolescent boys. We continue to fight to ensure all children have the same access to cancer prevention programs.

Building New Audiences & Awareness

Building New Audiences & Awareness

Collaboration and Advocacy

We continue to collaborate with new partners and expand our advocacy in exciting directions! This year, Executive Director and co-founder Justine Almada spoke on Capitol Hill about the importance of the HPV vaccine for National Cancer Prevention Day. We also partnered with Fxck Cancer on the red carpet at New York's Marquee Nightclub to end cancer, where we offered partygoers information on how to "Protect, Detect, and Unite" against HPV-related cancers. In September, Justine was featured in a video as a part of the American Cancer Society's efforts to raise awareness about the cancers caused by HPV.

Connecting the Professionals

Connecting the Professionals

Scientific collaboration

It's hard to believe that just a few years ago there was no such thing as a medical society for anal cancer doctors and researchers, and in November, the International Anal Neoplasia Society held its third international scientific meeting in San Francisco! The very first grant from the Foundation co-created this society to serve as a platform for global experts to advance prevention and treatment research. The strength of these forged connections was in full display this year as the meeting had its largest attendance yet. Doug Lowy, Acting Director of the National Cancer Institute, provided the keynote speech, while scientists from across the globe presented on the exciting developments they are making in both prevention and treatment. We were honored to organize the Thrivers in Action panel. Four intrepid thrivers spoke of their efforts to spread awareness of, and help others, with their anal cancer challenges

Supporting You

Supporting You

Peer-to-Peer Support

Our trailblazing Peer Support Program continues to grow! The program has opened newly diagnosed and recovering thrivers, as well as caregivers, to new resources, friends and support outlets. Such connections often deepen into true friendships, with thrivers traveling to meet each other in person and sending gifts across the globe. You can join the program on our website!